Panama Canal

Slice through Central America via the most famous canal in the world. With more than 900 species of birds, 10,000 species of plants, 1,350 plants and animals indigenous to the country and more species of mammals and amphibians than any other Central American country, Panama has one of the richest tropical environments on earth. Follow the footsteps of the conquistadors and immerse yourself in Panama's rich ecological and cultural diversity.

8 Night Panama Canal Cruise departing from Tampa, Florida

Carnival Cruise Line
Carnival Miracle
Ports of Call: Tampa, Florida | Puerto Limon, Costa Rica | Georgetown, Grand Cayman, Cayman Islands
Carnival Miracle

10 Night Carnival Journeys - Exotic Pan departing from Mobile, Alabama

Carnival Cruise Line
Carnival Fantasy
Ports of Call: Mobile, Alabama | Puerto Limon, Costa Rica | Roatan, Honduras | Cozumel, Mexico
Carnival Fantasy

10 Night Carnival Journeys - Panama Can departing from Tampa, Florida

Carnival Cruise Line
Carnival Paradise
Ports of Call: Tampa, Florida | Georgetown, Grand Cayman, Cayman Islands | Cartagena, Colombia | Puerto Limon, Costa Rica | Cozumel, Mexico
Carnival Paradise

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Caribbean Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Princess Cays, Bahamas | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands
Caribbean Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Caribbean Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Princess Cays, Bahamas | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Ocho Rios, Jamaica
Caribbean Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Caribbean Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Georgetown, Grand Cayman, Cayman Islands | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama
Caribbean Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Caribbean Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands
Caribbean Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Coral Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Port of Oranjestad, Aruba, Caribbean | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands
Coral Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Coral Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Port of Oranjestad, Aruba, Caribbean | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Ocho Rios, Jamaica
Coral Princess

10 NIGHT TRANSCANAL CRUISE departing from Miami, Florida

Oceania Cruises
Insignia
Ports of Call: Miami, Florida | Port of Oranjestad, Aruba, Caribbean | Willemstad, Curacao | Kralendijk, Bonaire, Dutch Antilles | St. Georges, Grenada, West Indies | Port of Kingstown, St. Vincent & the Grenadines | Castries, St. Lucia | Bridgetown, Barbados
Insignia

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Island Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands
Island Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Island Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Georgetown, Grand Cayman, Cayman Islands | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Ocho Rios, Jamaica
Island Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Island Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Ocho Rios, Jamaica | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands
Island Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Island Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Georgetown, Grand Cayman, Cayman Islands | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama
Island Princess

10 NIGHT TRANSCANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Island Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Grand Turk, Turks and Caicos | Cartagena, Spain | Gatun Lake, Panama Canal, Panama | Colon, Panama | Limon Bay Panama Canal, Panama | Ocho Rios, Jamaica
Island Princess

11 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Jade
Ports of Call: Miami, Florida | Cartagena, Colombia | Colon, Panama | Panama Canal/Gatun Lake, Panama | Puerto Limon, Costa Rica | Roatan, Honduras | Harvest Caye, Belize | Costa Maya, Mexico
Norwegian Jade

11 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Jade
Ports of Call: Miami, Florida | Cartagena, Colombia | Colon, Panama | Panama Canal/Gatun Lake, Panama | Puerto Limon, Costa Rica | Roatan, Honduras | Harvest Caye, Belize | Key West, Florida
Norwegian Jade

11 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Jade
Ports of Call: Miami, Florida | Colon, Panama | Panama Canal/Gatun Lake, Panama | Puerto Limon, Costa Rica | Roatan, Honduras | Santo Tomas de Castilla, Guatemala | Harvest Caye, Belize | Costa Maya, Mexico
Norwegian Jade

11 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Regent Seven Seas Cruises
Seven Seas Navigator
Ports of Call: Miami, Florida | Port Canaveral, Florida | Norfolk, Virginia | New York, New York | Halifax, Nova Scotia | Sept-Iles, Canada | Quebec City, Quebec | Montreal, Quebec
Seven Seas Navigator

11 NIGHT PANAMA CANAL & COSTA RICA departing from Miami, Florida

Azamara Club Cruises
Azamara Quest
Ports of Call: Miami, Florida | Havana, Cuba | Panama Canal, Panama | Fuerte Amador, Panama | Golfito, Costa Rica | Puerto Quepos, Costa Rica | Caldera (san Jose), Costa Rica | Puntarenas, Costa Rica
Azamara Quest

13 Night Carnival Journeys - Panama Can departing from Miami, Florida

Carnival Cruise Line
Carnival Splendor
Ports of Call: Miami, Florida | Cartagena, Colombia | Panama Canal, Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Cabo San Lucas, Mexico | Los Angeles, California
Carnival Splendor

14 Night Carnival Journeys - Panama Can departing from Galveston, Texas

Carnival Cruise Line
Carnival Freedom
Ports of Call: Galveston, Texas | Montego Bay, Jamaica | Port of Oranjestad, Aruba, Caribbean | Curacao, Caribbean | Cartagena, Colombia | Puerto Limon, Costa Rica | Cozumel, Mexico
Carnival Freedom

14 Night Carnival Journeys - Panama Can departing from Galveston, Texas

Carnival Cruise Line
Carnival Freedom
Ports of Call: Galveston, Texas | Georgetown, Grand Cayman, Cayman Islands | Port of Oranjestad, Aruba, Caribbean | Kralendijk, Bonaire, Dutch Antilles | Cartagena, Colombia | Puerto Limon, Costa Rica | Cozumel, Mexico
Carnival Freedom

14 Night Carnival Journeys - Panama Can departing from Los Angeles, California

Carnival Cruise Line
Carnival Miracle
Ports of Call: Los Angeles, California | Cabo San Lucas, Mexico | Puerto Quetzal, Guatemala | Puntarenas, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Georgetown, Grand Cayman, Cayman Islands | Tampa, Florida
Carnival Miracle

14 Night Carnival Journeys - Panama Can departing from Tampa, Florida

Carnival Cruise Line
Carnival Miracle
Ports of Call: Tampa, Florida | Cozumel, Mexico | Puerto Limon, Costa Rica | Cartagena, Colombia | Port of Oranjestad, Aruba, Caribbean | Curacao, Caribbean | Ocho Rios, Jamaica
Carnival Miracle

14-night Halloween On The High Seas Eastbound Panama Canal Cruise From San Diego To Galveston departing from San Diego, California

Disney Cruise Line
Disney Wonder
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Puerto Vallarta, Mexico | Panama Canal, Panama | Cartagena, Colombia | Georgetown, Grand Cayman, Cayman Islands | Cozumel, Mexico | Galveston, Texas
Disney Wonder

14-night Westbound Panama Canal Cruise From Port Canaveral departing from Port Canaveral, Florida

Disney Cruise Line
Disney Wonder
Ports of Call: Port Canaveral, Florida | Castaway Cay, Bahamas | Cartagena, Colombia | Punta Arenas, Chile | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Diego, California
Disney Wonder

14-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Maasdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Cabo San Lucas, Mexico | San Diego, California
Maasdam

14 NIGHT PANAMA CANAL CRUISE departing from Los Angeles, California

Norwegian Cruise Line
Norwegian Bliss
Ports of Call: Los Angeles, California | Puerto Vallarta, Mexico | Manzanillo, Mexico | Puerto Quetzal, Guatemala | Puntarenas, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Miami, Florida
Norwegian Bliss

14 NIGHT PANAMA CANAL CRUISE departing from Los Angeles, California

Norwegian Cruise Line
Norwegian Pearl
Ports of Call: Los Angeles, California | Cabo San Lucas, Mexico | Acapulco, Mexico | Huatulco, Mexico | Fort-de-France, Martinique | Panama Canal, Panama | Cartagena, Colombia | New Orleans, Louisiana
Norwegian Pearl

14 NIGHT PANAMA CANAL CRUISE departing from Tampa, Florida

Norwegian Cruise Line
Norwegian Pearl
Ports of Call: Tampa, Florida | Georgetown, Grand Cayman, Cayman Islands | Falmouth, Jamaica | Santa Marta, Colombia | Cartagena, Colombia | Colon, Panama | Panama Canal/Gatun Lake, Panama | Puerto Limon, Costa Rica | Santo Tomas de Castilla, Guatemala | Harvest Caye, Belize | Costa Maya, Mexico
Norwegian Pearl

14 NIGHT PANAMA CANAL CRUISE departing from Tampa, Florida

Norwegian Cruise Line
Norwegian Pearl
Ports of Call: Tampa, Florida | Georgetown, Grand Cayman, Cayman Islands | Ocho Rios, Jamaica | Santa Marta, Colombia | Cartagena, Colombia | Colon, Panama | Panama Canal/Gatun Lake, Panama | Puerto Limon, Costa Rica | Santo Tomas de Castilla, Guatemala | Harvest Caye, Belize | Costa Maya, Mexico
Norwegian Pearl

14 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Star
Ports of Call: Miami, Florida | Cartagena, Colombia | Panama Canal, Panama | Fort-de-France, Martinique | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Acapulco, Mexico | Cabo San Lucas, Mexico | Los Angeles, California
Norwegian Star

14 NIGHT PANAMA CANAL CRUISE departing from Los Angeles, California

Norwegian Cruise Line
Norwegian Star
Ports of Call: Los Angeles, California | Cabo San Lucas, Mexico | Acapulco, Mexico | Puerto Quetzal, Guatemala | San Juan del Sur, Nicaragua | Fort-de-France, Martinique | Panama Canal, Panama | Cartagena, Colombia | Miami, Florida
Norwegian Star

14 NIGHT PANAMA CANAL CRUISE departing from Los Angeles, California

Norwegian Cruise Line
Norwegian Star
Ports of Call: Los Angeles, California | Cabo San Lucas, Mexico | Acapulco, Mexico | San Juan del Sur, Nicaragua | Fort-de-France, Martinique | Panama Canal, Panama | Cartagena, Colombia | Georgetown, Grand Cayman, Cayman Islands | Miami, Florida
Norwegian Star

14 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Sun
Ports of Call: Miami, Florida | Cartagena, Colombia | Panama Canal, Panama | Fort-de-France, Martinique | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Acapulco, Mexico | Cabo San Lucas, Mexico | Los Angeles, California
Norwegian Sun

14 NIGHT PANAMA CANAL CRUISE departing from Los Angeles, California

Norwegian Cruise Line
Norwegian Sun
Ports of Call: Los Angeles, California | Cabo San Lucas, Mexico | Acapulco, Mexico | Puerto Quetzal, Guatemala | San Juan del Sur, Nicaragua | Fort-de-France, Martinique | Panama Canal, Panama | Cartagena, Colombia | Miami, Florida
Norwegian Sun

14-day Panama Canal departing from San Diego, California

Holland America Line
Oosterdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Fort Lauderdale (Port Everglades)
Oosterdam

14-day Panama Canal departing from San Diego, California

Holland America Line
Westerdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Fort Lauderdale (Port Everglades)
Westerdam

15-day Panama Canal Holiday departing from San Diego, California

Holland America Line
Amsterdam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Puerto Vallarta, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Amsterdam

15 Night Panama Canal - Ocean To Ocean departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Coral Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Port of Oranjestad, Aruba, Caribbean | Cartagena, Spain | Puntarenas, Costa Rica | San Juan del Sur, Nicaragua | Cabo San Lucas, Mexico | San Francisco, California
Coral Princess

15 NIGHT PANAMA CANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Coral Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Port of Oranjestad, Aruba, Caribbean | Cartagena, Spain | Fuerte Amador, Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Los Angeles, California
Coral Princess

15 NIGHT PANAMA CANAL CRUISE departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Coral Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Georgetown, Grand Cayman, Cayman Islands | Cartagena, Spain | Fuerte Amador, Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Los Angeles, California
Coral Princess

15 Night Panama Canal - Ocean To Ocean departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Coral Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Spain | Fuerte Amador, Panama | Puntarenas, Costa Rica | San Juan del Sur, Nicaragua | Cabo San Lucas, Mexico | San Francisco, California
Coral Princess

15 Night Panama Canal - Ocean To Ocean departing from Fort Lauderdale (Port Everglades)

Princess Cruises
Island Princess
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Spain | Fuerte Amador, Panama | Puntarenas, Costa Rica | San Juan del Sur, Nicaragua | Cabo San Lucas, Mexico | San Francisco, California
Island Princess

15-day Panama Canal departing from San Diego, California

Holland America Line
Maasdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Maasdam

15 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Bliss
Ports of Call: Miami, Florida | Cartagena, Colombia | Panama Canal, Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Los Angeles, California
Norwegian Bliss

15 NIGHT PANAMA CANAL CRUISE departing from Los Angeles, California

Norwegian Cruise Line
Norwegian Pearl
Ports of Call: Los Angeles, California | Cabo San Lucas, Mexico | Acapulco, Mexico | Puerto Quetzal, Guatemala | San Juan del Sur, Nicaragua | Fort-de-France, Martinique | Panama Canal, Panama | Cartagena, Colombia | Georgetown, Grand Cayman, Cayman Islands | Tampa, Florida
Norwegian Pearl

15 NIGHT PANAMA CANAL CRUISE departing from San Francisco, California

Norwegian Cruise Line
Norwegian Sun
Ports of Call: San Francisco, California | Cabo San Lucas, Mexico | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Fort-de-France, Martinique | Panama Canal, Panama | Cartagena, Colombia | Miami, Florida
Norwegian Sun

15 NIGHT PANAMA CANAL CRUISE departing from Miami, Florida

Norwegian Cruise Line
Norwegian Sun
Ports of Call: Miami, Florida | Cartagena, Colombia | Panama Canal, Panama | Fort-de-France, Martinique | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Acapulco, Mexico | Cabo San Lucas, Mexico | Ensenada, Mexico | Los Angeles, California
Norwegian Sun

15-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Oosterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Port of Oranjestad, Aruba, Caribbean | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Cabo San Lucas, Mexico | San Diego, California
Oosterdam

*From prices are per person, based on double occupancy and are cruise only. A 3.08% surcharge will apply for payments by Amex. A surcharge may apply for other card payments. Cruise guru charges a fee of $110 per person for cancellations and charges other fees in addition to any fees charged by cruise lines. Cancellation fees of up to 100% apply. View all fees and charges. Your exact price depends on the day of departure, departure city, ship and cabin. All offers and prices are for selected dates, sailings and cabin categories only and are subject to availability. Conditions apply.